The antibiotic (Vaccine)
Also called Phyllomedusa Bicolor or big monkey frog, it is found in the Amazon rainforest and is known for its healing and healing power. It is a substance that is extracted from the frog; to clarify, the frog is not harmed and is then returned to its natural habitat. The medicine is applied in the second layer of the skin, lifting the first layer (epidermis), through low intensity burns, we reach the second layer (dermis). With this technique we receive the medicine, a physical, emotional and spiritual purge. It is known that cells in acidic environments become carcinogenic, sick in all its possibilities. The acid (the toxic) is not only in food, drink, alcohol, tobacco, etc, but also in what you think, feel, say and do … Therefore, the Kambó is known as a potent antibiotic, releasing toxins, hormonal regulator, balances the PH leaving it alkaline, has a number of peptides very beneficial to the human body, capable of placing the immune system in an optimal state. The human cell has many characteristics, among them, the plasma membrane, cell membrane, cytoplasmic membrane or plasmalemma, is a layer or bilayer of phospholipids and other substances that delimits the entire cell, dividing the extracellular medium to the intracellular, which means that the membrane decides what enters and what does not. Well, the cell receives the properties of the kambó with total openness and confidence, as if it knew the benefit that awaits it. This is still in scientific studies, it has even been tried to synthesize without success, Mother Nature has reasons that reason ignores. I tell you this is the heaviest part for us to understand that we are facing an extraordinary natural medicine. It is said that it is not a “psychedelic or entheogenic” medicine, although, both my experience and that of thousands of participants report that they have mystical and out-of-body experiences. It is a medicine of the earth, of the roots, that goes beyond scientific and conventional medicine. The indigenous people consider it a very high spirit of healing.
The legend of Kampú – The shaman of Kaxinawa
It tells the story of a shaman named Kampú of the Kaxinawa tribe, who after several attempts with various plants, could not save the lives of his family and friends, they had an infection and no remedy prevented their deaths. Tired and dejected, he asked the “GREAT SPIRIT” for advice. He performed a ceremony with Ayahuasca and that was when he had the VISION, the grandmother showed him which frog it was, where it was and how to catch it, how to extract the poison and then apply it to people in that specific way. Indeed, that was how she was able to save her tribe and many more in the years to come, reaching the present time. This story is well known to the indigenous peoples throughout the Amazon. When Kampú died and his spirit left his body, it is said that the spirit of Kampú returned to the frog in which is found his healing and healing, from that moment is known as KAMBÓ (phyllomedusa bicolor).
There is another legend told by the natives, with whom I had the honor to share and extract in the middle of the jungle. When you go to the forest in search of the frog, you have to go with a purpose, an intention, a respect for healing, with humility and kindness, so that the frog can be seen and heard. The frog croaks in an exclusive and specific way. It is said and done that when you are on the edge of its habitat you have to sing it, you have to imitate its sound as close as you can. The frog will perceive your vibration and the feeling of your intentions, then it will decide whether to sing back to you, if so, it is inviting you to take it for its extraction and subsequent return to its place. If not, you will not be able to see it or find it. Science, mysticism, in any case it has its charm and seems to me a venerable being like all the Amazon.
Since 1966, many peptides existing in Kambo secretion have been isolated, characterized and synthesized, and as testimony to its medicinal properties there are more than 70 Kambo patents registered in the pharmaceutical world, mainly in the United States.
The main families of bioactive peptides identified in Kambo secretion so far include:
Philomedusins – such as Tachykinins (which also act as neuropeptides) – They produce contraction at the smooth muscle level and increase secretions throughout the gastrointestinal tract such as salivary glands, stomach, small and large intestine, pancreas and gall bladder. They are mainly responsible for the deep purge produced by the administration of kambo.
Philokinins and Philomedusins – both are potent vasodilators, increasing the permeability of the blood-brain barrier, both for their own access, as well as for other active peptides. Within this family are medusins, which also possess antimicrobial and antifungal properties.
Caeruleins and Sauvagins – These are peptides with chains of 40 amino acids, with myotropic properties on the smooth musculature, producing a contraction at the level of the colon and urinary bladder. They produce a drop in blood pressure accompanied by tachycardia. They stimulate the adrenal cortex and pituitary gland, contributing to greater sensory perception and increased endurance. Both peptides possess great analgesic power, contribute to increased physical strength, the ability to cope with physical pain, stress and illness, and decrease the symptoms of fatigue. In the medical field, this family of peptides contributes to improve digestion, and has analgesic properties against pain in renal colic, pain due to peripheral vascular insufficiency and tumor pain.
Dermorphins and deltorphins – These are small peptides composed of 7 amino acids. They are selective agonists of delta opioid receptors, 4000 times more potent than morphine and 40 times more potent than endogenous endorphins.
Adenoregulins – discovered in the 1990s by John Daly’s team at the National Institute of Health in the United States. Adenoregulin works in the human body through adenosine receptors, a key component in all human cellular fuel. These receptors may offer a target for the treatment of depression, stroke and cognitive loss diseases, such as Alzheimer’s disease and also Parkinson’s disease.
Antimicrobial peptides: Dermaseptins, including adenoregulins (with 33 amino acids), plasticins, and phyloseptins, are part of a family of broad-spectrum antimicrobial peptides involved in the defense of frogs’ bare skin against microbial invasion. These are the first vertebrate peptides to show lethal effects against filamentous fungi responsible for severe opportunistic infections, which accompany immunodeficiency syndrome and the use of immunosuppressive agents. They also show lethal effects against a broad spectrum of both gran+ and gran- bacteria, fungi, yeasts and protozoa. Several years of research conducted at the University of Paris have shown that Dermaseptin B2 and B3 peptides are effective in killing certain types of cancer cells. Research at Queens University, Belfast, recently won a prestigious award for their groundbreaking work with cancer and Kambo. Their mechanism of action occurs through inhibition of tumor cell angiogenesis, with selective cytotoxicity to these cells.
Bradykinins – such as phylloquinins and tryptophilins. They are peptides with structure and properties similar to human bradykinin. They are important sources of scientific study as they are hypotensive, produce vasodilatation, non-vascular smooth muscle contraction, increase vascular permeability and are also related to the mechanism of inflammatory pain.
Bombesins – these peptides stimulate hydrochloric acid secretion by acting on the G cells of the stomach, independently of the pH of the medium; they also increase pancreatic secretion, intestinal myoelectric activity and smooth muscle contractility.
Ceruleins – Stimulate gastric, biliary and pancreatic secretions, and certain smooth muscle. They could be used in paralytic ileus and as a diagnostic tool in pancreatic dysfunction.
Tryptophilins – are neuropeptides consisting of 4 to 14 amino acids, which are opening up new insights into how the human brain functions.